Sulforhodamine 101
Sulforhodamine 101
CAS: 60311-02-6
Molecular Formula: C31H30N2O7S2
Sulforhodamine 101 - Names and Identifiers
| Name | Sulforhodamine 101 |
| Synonyms | SR101 CI 45100 SULFORHODAMINE Sulforhodamine 101 SULFORHODAMINE 640 SULFORHODAMINE 101 SULFORHODAMINE 101 ACID Sulforhodamine 101 (free acid) |
| CAS | 60311-02-6 |
| EINECS | 262-159-4 |
Sulforhodamine 101 - Physico-chemical Properties
| Molecular Formula | C31H30N2O7S2 |
| Molar Mass | 606.71 |
| Density | 1.1982 (rough estimate) |
| Melting Point | >300°C |
| Solubility | Soluble in water (partly), methanol (1 mg/ml), DMSO, and DMF., Soluble in water (partly |
| Appearance | powder |
| Color | Dark Green |
| Maximum wavelength(λmax) | 579nm(CHCl3)(lit.) |
| BRN | 3582548 |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Sensitive to light |
| Refractive Index | 1.6900 (estimate) |
| MDL | MFCD00012407 |
| Use | A red-emitting flurophore used to label astrocytes. |
| In vitro study | Sulforhodamine 101 (SR101) does not label astrocytes in brainstem slices as strong and specific as in the hippocampus or cortex. To minimize excitatory side effects, the concentration of Sulforhodamine 101 has to be kept as low as possible or the labeling procedure can be performed after the actual experiment. |
| In vivo study | In vivo , epileptic activity can be induced by intra-hippocampal injection of small volumes of 10 μM Sulforhodamine 101 or topical application of 100 μM. |
Sulforhodamine 101 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8 |
| HS Code | 32049090 |
Sulforhodamine 101 - Reference Information
| application | sulforrhodamine 101 is an organic heterocyclic organic compound, which can be used as a fluorescent labeling dye. |
| biological activity | Sulforhodamine 101 (SR101) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Sulforhodamine 101 is widely used to study neuronal morphology and is used as a selective fluorescent marker for cell type of astrocytes, both in vivo and in slice preparation. |
| in vitro study | Sulforhodamine 101 (SR101) does not label astrocytes in brainstem slices as strong and specific as in the hippocampus or cortex. To minimize excitatory side effects, the concentration of Sulforhodamine 101 has to be kept as low as possible or the labeling procedure can be performed after the actual experiment. |
| in vivo study | in vivo , epileptic activity can be induced by intra-hippocampal injection of small volumes of 10 μ m Sulforhodamine 101 or topical application of 100 μ m. |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Last Update：2024-04-09 21:04:16
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